PLLPP1

Across TCGA patient cohorts, PLLPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,564 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLLPP1-associated GO terms across cancer lineages are Regulation of cilium assembly, Obsolete regulation of cytoplasmic transport, and Protein autoubiquitination. Each is linked with PLLPP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLLPP1-to-partner and partner-to-PLLPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by PLLPP1-low versus PLLPP1-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLLPP1→partner) and Y-score (partner→PLLPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Regulation of cilium assembly →	+0.043	+0.027	<.001	<.001	3	6
HNSC	Obsolete regulation of cytoplasmic transport →	+0.049	+0.055	<.001	<.001	3	6
HNSC	Protein autoubiquitination →	+0.046	+0.029	<.001	<.001	3	6
STAD	Transcription by RNA polymerase I →	+0.052	+0.111	<.001	<.001	3	6
HNSC	Amino acid metabolic process →	+0.037	+0.031	<.001	<.001	3	6
STAD	Intra-Golgi vesicle-mediated transport →	+0.043	+0.096	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,564 associations by consensus.

Regulation of cilium assembly by PLLPP1 expression — HNSC

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