PLK2

Across TCGA patient cohorts, PLK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,999 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLK2-associated proteins across cancer lineages are MMP2, P3H1, and PPFIBP1. Each is linked with PLK2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLK2-to-partner and partner-to-PLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLK2 versus MMP2 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLK2→partner) and Y-score (partner→PLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MMP2 →	+0.694	+1.084	<.001	<.001	3	8
LSCC	P3H1 →	+0.544	+0.709	<.001	<.001	3	7
OV	PPFIBP1 →	+0.457	+1.072	<.001	<.001	3	7
OV	CRTAP →	+0.542	+1.360	<.001	<.001	3	7
BRCA	ANGPTL2 →	+0.710	+1.039	<.001	<.001	3	6
OV	LUZP1 →	+0.379	+1.223	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,999 associations by consensus.

PLK2 vs MMP2 — OV

Explore this scatter interactively →