Across TCGA patient cohorts, PLIN5 mutation is significantly associated with the RNA expression of many other genes, with 792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLIN5-associated genes across cancer lineages are RNU6-1169P, MAGEB6B, and RNU6-604P. Each is linked with PLIN5 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLIN5-to-partner and partner-to-PLIN5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN5→partner) and Y-score (partner→PLIN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-1169P →	+0.240	+3.345	<.001	.008	3	3
PRAD	MAGEB6B →	+0.029	+7.939	<.001	.008	3	2
HNSC	RNU6-604P →	+0.633	+6.608	<.001	.001	3	2
UCEC	MOAP1 →	+0.529	+2.595	.007	.006	3	2
UCEC	NIPA1 →	+0.784	+3.459	.002	.005	3	2
UCEC	GON7 →	+0.697	+3.754	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

Exploration

PLIN5 survival (RNA) · tumor vs normal (RNA) · all PLIN5 data types