PLIN4

Across TCGA patient cohorts, PLIN4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,067 significant associations in total. OV shows the largest number of these associations.

The most reproducible PLIN4-associated genes across cancer lineages are HSPB7, RHOJ, and ITGA7. Each is linked with PLIN4 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLIN4-to-partner and partner-to-PLIN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLIN4 versus HSPB7 in HNSC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN4→partner) and Y-score (partner→PLIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HSPB7 →	+1.961	+0.963	<.001	<.001	3	9
UCEC	RHOJ →	+0.867	+0.784	<.001	<.001	3	8
BRCA	ITGA7 →	+1.068	+1.255	<.001	<.001	3	8
COAD	LMOD1 →	+1.494	+1.065	<.001	<.001	3	8
PDAC	PI16 →	+1.364	+1.262	<.001	<.001	3	8
LUAD	SHE →	+0.717	+0.401	.004	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,067 associations by consensus.

PLIN4 vs HSPB7 — HNSC

Explore this scatter interactively →