PLGRKT

Across TCGA cell cohorts, PLGRKT RNA expression is significantly associated with the go_rna of many other GO terms, with 2,943 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PLGRKT-associated GO terms across cancer lineages are Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Intraciliary transport involved in cilium assembly, and Protein delipidation. Each is linked with PLGRKT in more than 7 cancer types. Because this analysis shows association rather than direction, both PLGRKT-to-partner and partner-to-PLGRKT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by PLGRKT-low versus PLGRKT-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLGRKT→partner) and Y-score (partner→PLGRKT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	-0.093	-0.864	<.001	.003	3	8
SOFT_TISSUE	Intraciliary transport involved in cilium assembly →	+0.142	+1.184	<.001	<.001	3	8
STOMACH	Protein delipidation →	+0.082	+1.213	.003	.004	3	7
LUNG_NSCLC_LUAD	Pyrimidine ribonucleoside triphosphate metabolic process →	+0.076	+0.913	.008	<.001	3	7
LIVER	Regulation of plasminogen activation →	+0.244	+1.146	.001	<.001	2	8
KIDNEY	Cerebellar Purkinje cell differentiation →	+0.980	+0.877	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,943 associations by consensus.

Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by PLGRKT expression — STOMACH

Explore this box plot interactively →