Across TCGA patient cohorts, PLEKHG7 RNA expression is significantly associated with the RNA expression of many other genes, with 14,176 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PLEKHG7-associated genes across cancer lineages are DAPP1, ACSL5, and SPATA13. Each is linked with PLEKHG7 in more than 24 cancer types. Because this analysis shows association rather than direction, both PLEKHG7-to-partner and partner-to-PLEKHG7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHG7→partner) and Y-score (partner→PLEKHG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	DAPP1 →	+1.568	+0.425	<.001	.003	2	25
ESCA	ACSL5 →	+2.127	+0.399	<.001	<.001	3	23
ESCA	SPATA13 →	+1.153	+0.325	<.001	<.001	3	22
KICH	TRIM38 →	+0.926	+0.291	<.001	.001	3	22
SCLC	IRAG2 →	+2.067	+0.469	<.001	.001	3	22
UCEC	ARHGAP26 →	+1.157	+0.909	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,176 associations by consensus.

Exploration

PLEKHG7 survival (RNA) · tumor vs normal (RNA) · all PLEKHG7 data types