Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, PLEKHG7 mutation is significantly associated with the RNA expression of many other genes, with 933 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible PLEKHG7-associated genes across cancer lineages are B3GAT3, SLC4A2, and CHAF1A. Each is linked with PLEKHG7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLEKHG7-to-partner and partner-to-PLEKHG7 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (PLEKHG7→partner) and Y-score (partner→PLEKHG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.