Across TCGA cell cohorts, PLEKHG7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,322 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PLEKHG7-associated GO terms across cancer lineages are Lateral line system development, Acetylcholine biosynthetic process, and Negative regulation of T cell mediated cytotoxicity. Each is linked with PLEKHG7 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLEKHG7-to-partner and partner-to-PLEKHG7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHG7→partner) and Y-score (partner→PLEKHG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Lateral line system development →	+1.532	+0.197	.001	.003	3	7
STOMACH	Acetylcholine biosynthetic process →	+1.684	+0.186	<.001	.007	3	7
STOMACH	Negative regulation of T cell mediated cytotoxicity →	+1.267	+0.157	<.001	.003	3	6
STOMACH	Regulation of cytotoxic T cell degranulation →	+0.944	+0.157	.002	.003	3	6
STOMACH	Negative regulation of cytotoxic T cell degranulation →	+0.944	+0.157	.002	.003	3	6
CNS	Extrinsic apoptotic signaling pathway →	+0.049	+0.026	.001	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,322 associations by consensus.

Exploration

PLEKHG7 survival (RNA) · tumor vs normal (RNA) · all PLEKHG7 data types