PLEKHA8

Across TCGA cell cohorts, PLEKHA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,136 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLEKHA8-associated GO terms across cancer lineages are ER to Golgi ceramide transport, Ceramide 1-phosphate transport, and Nucleic acid transport. Each is linked with PLEKHA8 in more than 16 cancer types. Because this analysis shows association rather than direction, both PLEKHA8-to-partner and partner-to-PLEKHA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ER to Golgi ceramide transport grouped by PLEKHA8-low versus PLEKHA8-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA8→partner) and Y-score (partner→PLEKHA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ER to Golgi ceramide transport →	+0.142	+0.836	.002	<.001	3	17
KIDNEY	Ceramide 1-phosphate transport →	+0.146	+0.933	.001	.003	3	15
BONE	Nucleic acid transport →	+0.097	+0.776	<.001	<.001	3	13
BONE	RNA transport →	+0.097	+0.776	<.001	<.001	3	13
OESOPHAGUS	Establishment of RNA localization →	+0.103	+0.751	.009	.009	3	13
SOFT_TISSUE	Regulation of translational initiation →	+0.079	+0.996	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,136 associations by consensus.

ER to Golgi ceramide transport by PLEKHA8 expression — BLOOD_Leukemia

Explore this box plot interactively →