PLEKHA7

Across TCGA patient cohorts, PLEKHA7 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,341 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLEKHA7-associated proteins across cancer lineages are PLEKHA7_S612, PLEKHA7_S867, and PLEKHA7_S907. Each is linked with PLEKHA7 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLEKHA7-to-partner and partner-to-PLEKHA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHA7 versus PLEKHA7_S612 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA7→partner) and Y-score (partner→PLEKHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLEKHA7_S612 →	+0.804	+0.700	<.001	<.001	3	7
CCRCC	PLEKHA7_S867 →	+0.601	+0.719	<.001	.001	3	7
LSCC	PLEKHA7_S907 →	+0.742	+0.729	<.001	<.001	3	7
LSCC	HSPA13 →	-0.388	-0.502	<.001	.001	3	6
LUAD	PLEKHA7_S1063 →	+1.004	+0.755	<.001	<.001	3	6
LUAD	PLEKHA7_S536 →	+0.685	+0.606	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,341 associations by consensus.

PLEKHA7 vs PLEKHA7_S612 — LUAD

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