PLEKHA7

Across TCGA patient cohorts, PLEKHA7 protein abundance is significantly associated with the RNA expression of many other genes, with 11,312 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PLEKHA7-associated genes across cancer lineages are OR7E14P, C9orf152, and MAGI1. Each is linked with PLEKHA7 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLEKHA7-to-partner and partner-to-PLEKHA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHA7 versus OR7E14P in CCRCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA7→partner) and Y-score (partner→PLEKHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	OR7E14P →	+0.681	+0.369	<.001	<.001	3	8
UCEC	C9orf152 →	+1.535	+0.456	<.001	<.001	3	6
BRCA	MAGI1 →	+0.682	+0.416	.002	<.001	3	6
UCEC	SORBS2 →	+1.154	+0.390	<.001	<.001	3	6
BRCA	NDRG2 →	+0.924	+0.279	<.001	.006	3	6
BRCA	OCLN →	+0.757	+0.378	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,312 associations by consensus.

PLEKHA7 vs OR7E14P — CCRCC

Explore this scatter interactively →