PLEKHA6

Across TCGA patient cohorts, PLEKHA6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,131 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLEKHA6-associated proteins across cancer lineages are PLEKHA6_S459, PLEKHA6_S476, and PLEKHA6_S777. Each is linked with PLEKHA6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLEKHA6-to-partner and partner-to-PLEKHA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHA6 versus PLEKHA6_S459 in LSCC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA6→partner) and Y-score (partner→PLEKHA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA6_S459 →	+1.339	+1.235	<.001	<.001	3	7
LSCC	PLEKHA6_S476 →	+0.910	+0.873	<.001	<.001	3	7
PDAC	PLEKHA6_S777 →	+0.984	+0.754	<.001	<.001	3	7
LUAD	PLEKHA6_S808 →	+0.764	+0.963	<.001	<.001	3	7
LSCC	PLEKHA6_S940 →	+1.201	+1.356	<.001	<.001	3	7
LUAD	BROX →	+0.341	+0.962	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,131 associations by consensus.

PLEKHA6 vs PLEKHA6_S459 — LSCC

Explore this scatter interactively →