PLEKHA5

Across TCGA patient cohorts, PLEKHA5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,632 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLEKHA5-associated genes across cancer lineages are RN7SL67P, RN7SL459P, and LPCAT3. Each is linked with PLEKHA5 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLEKHA5-to-partner and partner-to-PLEKHA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHA5 versus RN7SL67P in GBM, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA5→partner) and Y-score (partner→PLEKHA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SL67P →	+1.473	+0.960	<.001	<.001	3	8
GBM	RN7SL459P →	+1.381	+0.856	<.001	<.001	3	7
OV	LPCAT3 →	+0.611	+0.305	<.001	<.001	3	6
HNSC	MANSC1 →	+1.116	+0.380	<.001	<.001	3	6
GBM	LTBR →	+0.888	+0.616	<.001	<.001	3	5
BRCA	MLKL →	-0.560	-0.349	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,632 associations by consensus.

PLEKHA5 vs RN7SL67P — GBM

Explore this scatter interactively →