PLCZ1

Across TCGA patient cohorts, PLCZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,910 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLCZ1-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Epithelial cell development, and Regulation of microtubule-based process. Each is linked with PLCZ1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PLCZ1-to-partner and partner-to-PLCZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by PLCZ1-low versus PLCZ1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCZ1→partner) and Y-score (partner→PLCZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Nuclear-transcribed mRNA catabolic process →	+0.055	+0.274	<.001	.005	3	13
STAD	Epithelial cell development →	+0.060	+0.210	<.001	<.001	3	13
STAD	Regulation of microtubule-based process →	+0.050	+0.212	<.001	<.001	3	13
TGCT	Cellular response to heat →	+0.050	+0.296	<.001	<.001	3	13
STAD	Negative regulation of protein catabolic process →	+0.061	+0.186	<.001	<.001	3	13
STAD	Protein polymerization →	+0.054	+0.193	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,910 associations by consensus.

Nuclear-transcribed mRNA catabolic process by PLCZ1 expression — SCLC

Explore this box plot interactively →