PLCH1-AS2

Across TCGA pan-cancer cohorts, PLCH1-AS2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PLCH1-AS2 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher PLCH1-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PLCH1-AS2 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

CHOL, LIHC, and OV are the cancer types where PLCH1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	II,III,IV	0.194	0.782	.002	75	view →
LIHC	OS	Tertile	II,III,IV	0.154	0.706	<.001	51	view →
OV	DFS	Tertile	II,III,IV	0.452	0.357	.014	48	view →
ESCA	OS	Quartile	II,III,IV	0.749	0.372	<.001	41	view →
PCPG	DFS	Tertile	All	0.073	0.856	.001	21	view →
SARC	DFS	Tertile	All	0.103	0.405	.001	21	view →
COAD	DFS	Tertile	IV	0.236	0.551	.002	18	view →
UVM	OS	Tertile	All	0.549	0.785	.013	18	view →
STAD	OS	Median	III,IV	0.694	0.563	.018	15	view →
KIRC	DFS	Tertile	II,III,IV	0.883	0.689	.013	14	view →
LUSC	OS	Quartile	II,III,IV	0.950	0.611	.009	13	view →
UCS	DFS	Tertile	All	0.488	0.230	.031	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PLCH1-AS2–CHOL (OS)

Open the CHOL breakdown →