PLCH1-AS1

Across TCGA pan-cancer cohorts, PLCH1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PLCH1-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PLCH1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PLCH1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

BLCA, OV, and UVM are the cancer types where PLCH1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.611	0.347	<.001	98	view →
OV	OS	Tertile	All	0.397	0.294	.003	72	view →
UVM	OS	Quartile	All	0.902	0.515	.003	51	view →
STAD	OS	Quartile	All	0.790	0.550	<.001	38	view →
LAML	DFS	Quartile	All	0.784	0.497	<.001	32	view →
KIRP	DFS	Median	All	0.938	0.589	<.001	30	view →
SKCM	OS	Quartile	III,IV	0.235	0.434	.002	29	view →
PCPG	OS	Tertile	All	0.768	0.980	<.001	27	view →
LIHC	OS	Tertile	All	0.222	0.528	<.001	27	view →
ESCA	OS	Median	All	0.418	1.000	.005	20	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
MESO	OS	Tertile	III,IV	0.312	0.577	.022	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PLCH1-AS1–BLCA (OS)

Open the BLCA breakdown →