Across TCGA cell cohorts, PLCG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,062 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PLCG2-associated GO terms across cancer lineages are Antifungal innate immune response, Response to yeast, and Regulation of RNA splicing. Each is linked with PLCG2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PLCG2-to-partner and partner-to-PLCG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCG2→partner) and Y-score (partner→PLCG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Antifungal innate immune response →	-0.230	-1.843	<.001	<.001	3	12
STOMACH	Response to yeast →	-0.212	-1.625	<.001	<.001	3	11
OESOPHAGUS	Regulation of RNA splicing →	+0.075	+0.982	.001	<.001	3	10
OESOPHAGUS	RNA catabolic process →	+0.059	+0.983	<.001	<.001	3	10
OESOPHAGUS	Regulation of myoblast fusion →	+0.104	+0.841	.004	.001	3	10
OESOPHAGUS	Negative regulation of mRNA metabolic process →	+0.074	+0.942	.004	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,062 associations by consensus.

Exploration

PLCG2 survival (RNA) · tumor vs normal (RNA) · all PLCG2 data types