PLCE1-AS2

Across TCGA pan-cancer cohorts, PLCE1-AS2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated PLCE1-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PLCE1-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PLCE1-AS2 expression acts as an unfavorable survival marker, although some lineages such as SARC and BRCA show a favorable association.

KIRC, READ, and ESCA are the cancer types where PLCE1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.526	0.692	<.001	106	view →
READ	DFS	Tertile	IV	0.125	0.700	<.001	42	view →
ESCA	OS	Median	All	0.418	1.000	.005	35	view →
COAD	OS	Median	II,III,IV	0.688	0.857	.001	21	view →
SARC	DFS	Tertile	All	0.671	0.475	.016	14	view →
LGG	OS	Median	All	0.713	0.898	<.001	11	view →
BRCA	OS	Quartile	III,IV	0.693	0.498	.034	10	view →
ACC	DFS	Tertile	III,IV	1.000	0.385	.022	9	view →
TGCT	DFS	Median	II,III,IV	0.711	0.996	.022	6	view →
KIRP	OS	Tertile	All	0.828	0.920	.021	6	view →
LAML	DFS	Tertile	All	0.807	0.520	.041	6	view →
STAD	OS	Median	All	0.730	0.601	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

PLCE1-AS2–KIRC (OS)

Open the KIRC breakdown →