PLCD4

Across TCGA patient cohorts, PLCD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,982 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLCD4-associated proteins across cancer lineages are SGCB, RPL5, and SLTM. Each is linked with PLCD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLCD4-to-partner and partner-to-PLCD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCD4 versus SGCB in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCD4→partner) and Y-score (partner→PLCD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SGCB →	+0.754	+0.649	<.001	<.001	3	5
BRCA	RPL5 →	-0.264	-0.731	<.001	<.001	3	4
OV	SLTM →	-0.228	-0.146	.006	.002	3	4
UCEC	LAMA4 →	+0.546	+0.414	<.001	.003	3	4
PDAC	SEPTIN8 →	+0.270	+0.172	.002	.004	3	4
COAD	SGCD →	+0.714	+0.144	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,982 associations by consensus.

PLCD4 vs SGCB — HNSC

Explore this scatter interactively →