PLCB2-AS1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLCB2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,787 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PLCB2-AS1-associated GO terms across cancer lineages are T cell proliferation, Positive regulation of leukocyte cell-cell adhesion, and Lymphocyte activation involved in immune response. Each is linked with PLCB2-AS1 in more than 26 cancer types. Because this analysis shows association rather than direction, both PLCB2-AS1-to-partner and partner-to-PLCB2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell proliferation grouped by PLCB2-AS1-low versus PLCB2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCB2-AS1→partner) and Y-score (partner→PLCB2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAT cell proliferation →+0.058+0.108<.001<.001327
ESCAPositive regulation of leukocyte cell-cell adhesion →+0.048+0.077<.001<.001326
ESCALymphocyte activation involved in immune response →+0.045+0.081<.001<.001326
ESCAT cell activation involved in immune response →+0.053+0.123<.001<.001326
ESCARegulation of B cell activation →+0.053+0.101<.001<.001325
ESCANegative regulation of cell activation →+0.047+0.079<.001<.001325
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,787 associations by consensus.

T cell proliferation by PLCB2-AS1 expression — ESCA

Box plot of T cell proliferation in PLCB2-AS1-low vs PLCB2-AS1-high samples in ESCA.

Explore this box plot interactively →

Exploration