PLCB2-AS1

Across TCGA pan-cancer cohorts, PLCB2-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated PLCB2-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher PLCB2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PLCB2-AS1 expression acts as an unfavorable survival marker, although some lineages such as STAD and UVM show a favorable association.

KICH, COAD, and LUAD are the cancer types where PLCB2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	II,III,IV	0.043	0.950	<.001	69	view →
COAD	OS	Tertile	All	0.362	0.632	<.001	57	view →
LUAD	DFS	Tertile	IV	0.497	0.848	.003	38	view →
LGG	OS	Tertile	All	0.728	0.844	<.001	37	view →
LIHC	OS	Tertile	All	0.553	0.729	.006	30	view →
STAD	OS	Tertile	II,III,IV	0.703	0.458	.025	23	view →
UCS	DFS	Tertile	IV	0.321	0.805	.012	18	view →
UVM	OS	Median	All	0.835	0.570	.006	18	view →
LUSC	DFS	Quartile	III,IV	0.682	0.226	.004	12	view →
HNSC	DFS	Tertile	IV	0.638	0.506	.024	12	view →
READ	OS	Tertile	IV	0.077	1.000	.014	9	view →
KIRC	DFS	Quartile	All	0.735	0.813	.006	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

PLCB2-AS1–KICH (DFS)

Open the KICH breakdown →