PLBD1-AS1

Across TCGA pan-cancer cohorts, PLBD1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PLBD1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PLBD1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PLBD1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, LGG, and LIHC are the cancer types where PLBD1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.711	0.550	<.001	94	view →
LGG	OS	Median	All	0.718	0.899	<.001	53	view →
LIHC	OS	Quartile	All	0.390	0.660	<.001	46	view →
PAAD	OS	Tertile	II,III,IV	0.302	0.630	.003	35	view →
HNSC	DFS	Median	IV	0.711	0.568	.002	33	view →
UVM	OS	Quartile	All	0.448	0.888	.013	29	view →
SKCM	OS	Tertile	IV	0.613	0.119	<.001	27	view →
ACC	DFS	Tertile	II,III,IV	0.684	0.296	.015	24	view →
UCEC	DFS	Quartile	All	0.451	0.779	.006	24	view →
ESCA	OS	Median	II,III,IV	0.445	0.637	.016	22	view →
STAD	DFS	Tertile	IV	0.149	0.617	.001	21	view →
KIRP	DFS	Tertile	III,IV	0.809	0.220	.021	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PLBD1-AS1–KIRC (DFS)

Open the KIRC breakdown →