PLB1

Across TCGA patient cohorts, PLB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,983 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLB1-associated proteins across cancer lineages are SERPINB8, CRYBG3, and STAB1. Each is linked with PLB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLB1-to-partner and partner-to-PLB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLB1 versus SERPINB8 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLB1→partner) and Y-score (partner→PLB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINB8 →	+0.598	+0.756	<.001	<.001	3	4
BRCA	CRYBG3 →	+0.412	+0.586	<.001	<.001	3	4
CCRCC	STAB1 →	+0.480	+0.388	<.001	.002	3	4
GBM	VSIG4 →	+0.868	+0.686	<.001	<.001	3	4
COAD	LARP1_S151 →	-0.406	-0.355	.004	.001	3	3
CCRCC	PROS1 →	+0.503	+0.303	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,983 associations by consensus.

PLB1 vs SERPINB8 — GBM

Explore this scatter interactively →