PLAUR

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLAUR mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PLAUR-associated genes across cancer lineages are LCE2A. Each is linked with PLAUR in more than 1 cancer types. Because this analysis shows association rather than direction, both PLAUR-to-partner and partner-to-PLAUR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE2A grouped by PLAUR-low versus PLAUR-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAUR→partner) and Y-score (partner→PLAUR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaLCE2A →+0.038+5.209<.001.00531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

LCE2A by PLAUR expression — BLOOD_Lymphoma

Box plot of LCE2A in PLAUR-low vs PLAUR-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration