PLAGL2

Across TCGA patient cohorts, PLAGL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,763 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLAGL2-associated proteins across cancer lineages are RALY, DHX9, and NCOA5. Each is linked with PLAGL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLAGL2-to-partner and partner-to-PLAGL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLAGL2 versus RALY in COAD, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAGL2→partner) and Y-score (partner→PLAGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RALY →	+0.493	+1.356	<.001	<.001	3	9
LSCC	DHX9 →	+0.244	+0.794	<.001	<.001	3	7
GBM	NCOA5 →	+0.234	+0.435	<.001	<.001	3	6
HNSC	PARP1 →	+0.376	+0.653	.001	.001	3	6
UCEC	WDR43 →	+0.317	+0.795	<.001	<.001	3	6
GBM	WDR5 →	+0.293	+0.467	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,763 associations by consensus.

PLAGL2 vs RALY — COAD

Explore this scatter interactively →