PLAAT5

Across TCGA patient cohorts, PLAAT5 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,139 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLAAT5-associated proteins across cancer lineages are KMT2D_S4738, PLAAT3, and REEP4_S152. Each is linked with PLAAT5 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLAAT5-to-partner and partner-to-PLAAT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLAAT5 versus KMT2D_S4738 in OV, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAAT5→partner) and Y-score (partner→PLAAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KMT2D_S4738 →	-0.415	-0.431	.006	.004	3	4
LUAD	PLAAT3 →	+0.788	+0.810	<.001	.003	3	4
BRCA	REEP4_S152 →	-0.609	-1.189	.001	.002	3	4
OV	AKAP12_S1512 →	+1.287	+1.585	.003	<.001	3	4
OV	PRKG1 →	+0.684	+0.753	<.001	<.001	3	3
COAD	PYGL →	+0.487	+0.653	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,139 associations by consensus.

PLAAT5 vs KMT2D_S4738 — OV

Explore this scatter interactively →