PLA2R1

Across TCGA cell cohorts, PLA2R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,056 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLA2R1-associated GO terms across cancer lineages are Regulation of protein localization to cell periphery, Protein targeting, and Regulation of myoblast fusion. Each is linked with PLA2R1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PLA2R1-to-partner and partner-to-PLA2R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to cell periphery grouped by PLA2R1-low versus PLA2R1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2R1→partner) and Y-score (partner→PLA2R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein localization to cell periphery →	+0.103	+1.361	<.001	<.001	3	12
OVARY	Protein targeting →	+0.051	+1.062	.001	<.001	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.117	+1.356	.004	.004	2	13
BONE	Regulation of protein localization to membrane →	+0.121	+1.627	<.001	<.001	3	12
KIDNEY	Regulation of steroid biosynthetic process →	+0.107	+1.504	<.001	<.001	3	12
BONE	Protein localization to membrane →	+0.094	+1.299	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,056 associations by consensus.

Regulation of protein localization to cell periphery by PLA2R1 expression — BONE

Explore this box plot interactively →