Across TCGA patient cohorts, PLA2G6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,875 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLA2G6-associated proteins across cancer lineages are VEZF1, NRBF2, and PLAU. Each is linked with PLA2G6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLA2G6-to-partner and partner-to-PLA2G6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G6→partner) and Y-score (partner→PLA2G6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VEZF1 →	+0.400	+0.562	<.001	<.001	3	7
BRCA	NRBF2 →	-0.383	-0.824	<.001	<.001	3	6
GBM	PLAU →	-0.736	-0.444	<.001	.001	3	6
GBM	CBX8 →	+0.382	+0.437	<.001	<.001	3	6
LSCC	HNRNPU →	+0.205	+0.620	<.001	<.001	3	6
BRCA	MSI2 →	+0.432	+0.648	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,875 associations by consensus.

Exploration

PLA2G6 survival (RNA) · tumor vs normal (RNA) · all PLA2G6 data types