Across TCGA patient cohorts, PLA2G6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,606 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLA2G6-associated genes across cancer lineages are CBY1, GRIK2, and EIF3L. Each is linked with PLA2G6 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLA2G6-to-partner and partner-to-PLA2G6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G6→partner) and Y-score (partner→PLA2G6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CBY1 →	+0.360	+0.495	.001	.001	3	3
GBM	GRIK2 →	+1.254	+0.268	<.001	.002	3	3
BRCA	EIF3L →	+0.482	+0.270	<.001	.004	3	2
LSCC	DNAL4 →	+0.384	+0.302	<.001	<.001	3	2
LSCC	MIEF1 →	+0.394	+0.475	.002	.001	3	2
LSCC	EIF3D →	+0.330	+0.399	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,606 associations by consensus.

Exploration

PLA2G6 survival (RNA) · tumor vs normal (RNA) · all PLA2G6 data types