PLA2G5

Across TCGA patient cohorts, PLA2G5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,269 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLA2G5-associated genes across cancer lineages are AHCY, POP1, and EZH2. Each is linked with PLA2G5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G5-to-partner and partner-to-PLA2G5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G5 versus AHCY in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G5→partner) and Y-score (partner→PLA2G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AHCY →	-0.866	-0.671	.001	<.001	3	2
LUAD	POP1 →	-0.638	-0.581	<.001	.001	3	2
LSCC	EZH2 →	-0.945	-0.729	<.001	<.001	3	2
LUAD	PDE1A →	+0.790	+0.609	<.001	.002	3	2
LUAD	RGS2 →	+0.832	+0.633	<.001	<.001	3	2
LSCC	TRIM24 →	-0.747	-0.758	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,269 associations by consensus.

PLA2G5 vs AHCY — LSCC

Explore this scatter interactively →