PLA2G5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLA2G5 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PLA2G5-associated genes across cancer lineages are CD300LD. Each is linked with PLA2G5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G5-to-partner and partner-to-PLA2G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300LD grouped by PLA2G5-low versus PLA2G5-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G5→partner) and Y-score (partner→PLA2G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCCD300LD →+0.022+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD300LD by PLA2G5 expression — LUNG_SCLC

Box plot of CD300LD in PLA2G5-low vs PLA2G5-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration