PLA2G4E

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLA2G4E protein abundance is significantly associated with the RNA expression of many other genes, with 7,899 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLA2G4E-associated genes across cancer lineages are TAS2R9, SUV39H1, and PHF3. Each is linked with PLA2G4E in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G4E-to-partner and partner-to-PLA2G4E results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4E→partner) and Y-score (partner→PLA2G4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTAS2R9 →-0.295-0.772<.001<.00132
HNSCSUV39H1 →-0.643-0.879<.001<.00132
HNSCPHF3 →-0.503-0.812<.001<.00132
HNSCB4GALT4 →-0.845-0.899.001<.00132
HNSCMCM8 →-0.725-1.131.001<.00132
HNSCSLC15A2 →-0.789-0.983.004.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,899 associations by consensus.

Exploration