PLA2G4E

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLA2G4E RNA expression is significantly associated with the go_rna of many other GO terms, with 1,431 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PLA2G4E-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Desmosome maintenance, and Viral budding. Each is linked with PLA2G4E in more than 5 cancer types. Because this analysis shows association rather than direction, both PLA2G4E-to-partner and partner-to-PLA2G4E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4E→partner) and Y-score (partner→PLA2G4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHCytotoxic T cell degranulation →+0.271+0.063.001.00936
STOMACHDesmosome maintenance →+0.622+0.079.006<.00136
OVARYViral budding →+0.060+0.015.002.00826
UPPER_AERODIGESTIVE_TRACTCopulation →+0.795+0.608.001.00135
UPPER_AERODIGESTIVE_TRACTPurkinje myocyte action potential →+0.796+0.885.005.00535
UPPER_AERODIGESTIVE_TRACTMembrane depolarization during Purkinje myocyte cell action potential →+0.796+0.885.005.00535
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,431 associations by consensus.

Exploration