PLA2G4C

Across TCGA patient cohorts, PLA2G4C protein abundance is significantly associated with the RNA expression of many other genes, with 10,126 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLA2G4C-associated genes across cancer lineages are RCSD1, SENCR, and PPP1R16B. Each is linked with PLA2G4C in more than 4 cancer types. Because this analysis shows association rather than direction, both PLA2G4C-to-partner and partner-to-PLA2G4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G4C versus RCSD1 in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4C→partner) and Y-score (partner→PLA2G4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCSD1 →	+0.886	+0.598	<.001	<.001	3	5
UCEC	SENCR →	+0.758	+0.649	<.001	<.001	3	5
GBM	PPP1R16B →	+1.571	+0.638	<.001	<.001	3	4
UCEC	IFFO1 →	+0.624	+0.608	<.001	<.001	3	4
LSCC	RASAL3 →	+0.851	+0.579	<.001	<.001	3	4
LSCC	BIN2 →	+0.863	+0.607	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,126 associations by consensus.

PLA2G4C vs RCSD1 — LSCC

Explore this scatter interactively →