PLA2G4C

Across TCGA cell cohorts, PLA2G4C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,831 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLA2G4C-associated GO terms across cancer lineages are Positive regulation of canonical NF-kappaB signal transduction, Viral process, and Regulation of extrinsic apoptotic signaling pathway via death domain receptors. Each is linked with PLA2G4C in more than 12 cancer types. Because this analysis shows association rather than direction, both PLA2G4C-to-partner and partner-to-PLA2G4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical NF-kappaB signal transduction grouped by PLA2G4C-low versus PLA2G4C-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4C→partner) and Y-score (partner→PLA2G4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of canonical NF-kappaB signal transduction →	+0.062	+1.256	<.001	.007	3	13
SOFT_TISSUE	Viral process →	+0.087	+1.506	<.001	<.001	3	12
LIVER	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.181	+2.949	.001	<.001	3	12
LUNG_NSCLC_LUAD	Amino acid catabolic process →	-0.079	-1.256	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein catabolic process →	+0.037	+0.895	.005	.005	3	11
SOFT_TISSUE	Regulation of tumor necrosis factor production →	+0.082	+1.225	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,831 associations by consensus.

Positive regulation of canonical NF-kappaB signal transduction by PLA2G4C expression — PANCREAS

Explore this box plot interactively →