PLA2G4C-AS1

Across TCGA pan-cancer cohorts, PLA2G4C-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PLA2G4C-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PLA2G4C-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PLA2G4C-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and CHOL show a favorable association.

KIRC, UVM, and CESC are the cancer types where PLA2G4C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.476	0.738	<.001	102	view →
UVM	DFS	Tertile	III,IV	0.345	0.870	<.001	89	view →
CESC	OS	Tertile	IV	0.723	0.260	.018	34	view →
UCS	OS	Quartile	III,IV	0.259	0.754	<.001	26	view →
THYM	DFS	Tertile	III,IV	0.461	1.000	.005	18	view →
LGG	DFS	Tertile	All	0.785	0.883	<.001	18	view →
MESO	OS	Quartile	II,III,IV	0.163	0.395	.010	16	view →
CHOL	DFS	Median	All	0.858	0.128	.003	15	view →
LUSC	DFS	Quartile	III,IV	0.729	0.286	.001	15	view →
BRCA	DFS	Median	II,III,IV	0.924	0.957	.008	14	view →
KIRP	DFS	Median	II,III,IV	0.928	0.544	.020	12	view →
DLBC	OS	Median	All	0.569	1.000	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PLA2G4C-AS1–KIRC (DFS)

Open the KIRC breakdown →