PLA2G4C-AS1

Across TCGA pan-cancer cohorts, PLA2G4C-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of PLA2G4C-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PLA2G4C-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PLA2G4C-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, LIHC, and BRCA are the cancer types where PLA2G4C-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PLA2G4C-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.199	<.001	9	view →
LIHC	Female	II,III,IV	+0.403	<.001	8	view →
BRCA	All	All	+0.386	<.001	6	view →
COAD	All	III,IV	+0.229	.021	6	view →
THCA	Male	All	−0.151	<.001	4	view →
KICH	All	All	+0.114	.010	3	view →
PRAD	All	All	+1.282	<.001	2	view →
CHOL	All	All	+0.747	.006	2	view →
LUAD	All	IV	+0.240	.015	2	view →
ESCA	Female	All	+0.229	.034	1	view →
HNSC	Female	II,III,IV	+0.120	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

PLA2G4C-AS1–KIRC

Open the KIRC breakdown →