Across TCGA patient cohorts, PLA2G2E mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PLA2G2E-associated genes across cancer lineages are FAR1P1, RNA5SP146, and ZNF555. Each is linked with PLA2G2E in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G2E-to-partner and partner-to-PLA2G2E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G2E→partner) and Y-score (partner→PLA2G2E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAR1P1 →	+0.112	+4.426	<.001	.006	3	2
SKCM	RNA5SP146 →	+0.346	+5.867	<.001	.003	3	2
UCEC	ZNF555 →	+0.399	+3.250	.008	.008	3	1
UCEC	RNU6-1082P →	+0.401	+3.966	<.001	<.001	3	1
UCEC	RNU6-32P →	+0.468	+2.496	.009	.007	3	1
UCEC	RNU6-4P →	+0.570	+2.653	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

Exploration

PLA2G2E survival (RNA) · tumor vs normal (RNA) · all PLA2G2E data types