Across TCGA cell cohorts, PLA2G2E RNA expression is significantly associated with the mutation status of many other genes, with 49 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PLA2G2E-associated genes across cancer lineages are NLRP13, COL5A1, and ANKAR. Each is linked with PLA2G2E in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G2E-to-partner and partner-to-PLA2G2E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G2E→partner) and Y-score (partner→PLA2G2E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	NLRP13 →	+4.392	+0.285	.003	<.001	3	2
LUNG_SCLC	COL5A1 →	+3.817	+0.443	.004	<.001	3	2
LUNG_SCLC	ANKAR →	+4.817	+0.562	.001	<.001	3	2
OESOPHAGUS	WNK1 →	+4.392	+0.285	.003	<.001	3	1
PANCREAS	TEP1 →	+4.786	+0.095	.001	<.001	3	1
PANCREAS	VPS13B →	+4.786	+0.089	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

PLA2G2E survival (RNA) · tumor vs normal (RNA) · all PLA2G2E data types