PLA2G2D

Across TCGA patient cohorts, PLA2G2D mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLA2G2D-associated genes across cancer lineages are RN7SKP128, LINC01766, and SGO1-AS1. Each is linked with PLA2G2D in more than 1 cancer types. Because this analysis shows association rather than direction, both PLA2G2D-to-partner and partner-to-PLA2G2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP128 grouped by PLA2G2D-low versus PLA2G2D-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G2D→partner) and Y-score (partner→PLA2G2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP128 →	+0.049	+4.186	<.001	.007	3	1
SKCM	LINC01766 →	+0.238	+2.838	<.001	.004	3	1
SKCM	SGO1-AS1 →	+0.043	+3.496	.001	<.001	3	1
HNSC	UBTFL3 →	+0.079	+7.954	<.001	.008	3	1
UCEC	INSL4 →	+1.012	+3.753	<.001	.004	3	1
UCEC	SLCO1B1 →	+0.306	+3.099	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

RN7SKP128 by PLA2G2D expression — SKCM

Explore this box plot interactively →