Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, PLA2G2A mutation is significantly associated with the RNA expression of many other genes, with 522 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible PLA2G2A-associated genes across cancer lineages are RPL22P8, ORC5, and METTL2B. Each is linked with PLA2G2A in more than 2 cancer types. Because this analysis shows association rather than direction, both PLA2G2A-to-partner and partner-to-PLA2G2A results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (PLA2G2A→partner) and Y-score (partner→PLA2G2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.