PLA2G12B

Across TCGA patient cohorts, PLA2G12B protein abundance is significantly associated with the RNA expression of many other genes, with 7,069 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLA2G12B-associated genes across cancer lineages are SDC4, FBN2, and ESYT3. Each is linked with PLA2G12B in more than 2 cancer types. Because this analysis shows association rather than direction, both PLA2G12B-to-partner and partner-to-PLA2G12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G12B versus SDC4 in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G12B→partner) and Y-score (partner→PLA2G12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SDC4 →	+0.758	+0.979	<.001	<.001	3	3
LSCC	FBN2 →	-1.369	-0.393	.007	.004	3	3
LUAD	ESYT3 →	+1.110	+0.914	<.001	<.001	3	3
CCRCC	ABCC6P1 →	+1.058	+0.747	<.001	<.001	3	3
LUAD	LRP2 →	+1.658	+1.132	<.001	<.001	3	3
CCRCC	ABCC6 →	+1.205	+0.785	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,069 associations by consensus.

PLA2G12B vs SDC4 — CCRCC

Explore this scatter interactively →