PLA2G12A

Across TCGA patient cohorts, PLA2G12A protein abundance is significantly associated with the RNA expression of many other genes, with 2,763 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLA2G12A-associated genes across cancer lineages are SBDSP1, CDC37, and CACNG1. Each is linked with PLA2G12A in more than 2 cancer types. Because this analysis shows association rather than direction, both PLA2G12A-to-partner and partner-to-PLA2G12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G12A versus SBDSP1 in LUAD, with a Pearson correlation of -0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G12A→partner) and Y-score (partner→PLA2G12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SBDSP1 →	-0.742	-0.739	.005	.001	3	3
LUAD	CDC37 →	-0.445	-0.637	.005	.002	3	2
LUAD	CACNG1 →	-0.470	-0.839	.001	<.001	3	2
UCEC	KIAA0513 →	-0.862	-0.770	.005	<.001	3	2
BRCA	GBGT1 →	-1.065	-0.962	.008	.004	3	2
HNSC	SNORD127 →	-1.788	-0.413	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,763 associations by consensus.

PLA2G12A vs SBDSP1 — LUAD

Explore this scatter interactively →