PLA2G10

Across TCGA cell cohorts, PLA2G10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,992 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PLA2G10-associated GO terms across cancer lineages are Cellular response to alcohol, Platelet activating factor catabolic process, and Ether catabolic process. Each is linked with PLA2G10 in more than 10 cancer types. Because this analysis shows association rather than direction, both PLA2G10-to-partner and partner-to-PLA2G10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to alcohol grouped by PLA2G10-low versus PLA2G10-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G10→partner) and Y-score (partner→PLA2G10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cellular response to alcohol →	+0.185	+1.248	<.001	.003	3	11
OESOPHAGUS	Platelet activating factor catabolic process →	-0.238	-1.123	<.001	<.001	3	11
OESOPHAGUS	Ether catabolic process →	-0.238	-1.123	<.001	<.001	3	11
OESOPHAGUS	Glycerol ether catabolic process →	-0.238	-1.123	<.001	<.001	3	11
STOMACH	Response to indole-3-methanol →	+0.251	+1.293	<.001	<.001	3	10
OESOPHAGUS	Positive regulation of arachidonate secretion →	-0.317	-1.447	.003	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,992 associations by consensus.

Cellular response to alcohol by PLA2G10 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →