PKIG

Across TCGA patient cohorts, PKIG protein abundance is significantly associated with the RNA expression of many other genes, with 17,029 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PKIG-associated genes across cancer lineages are CDC20, CASQ2, and KIF2C. Each is linked with PKIG in more than 6 cancer types. Because this analysis shows association rather than direction, both PKIG-to-partner and partner-to-PKIG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKIG versus CDC20 in BRCA, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PKIG→partner) and Y-score (partner→PKIG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC20 →	-1.155	-0.362	<.001	<.001	3	7
HNSC	CASQ2 →	+2.205	+0.393	<.001	<.001	3	7
BRCA	KIF2C →	-1.438	-0.564	<.001	<.001	3	7
UCEC	SPARCL1 →	+1.369	+0.448	<.001	<.001	3	7
OV	PABPC5 →	+0.659	+0.421	<.001	<.001	3	7
UCEC	TCEAL7 →	+1.186	+0.403	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,029 associations by consensus.

PKIG vs CDC20 — BRCA

Explore this scatter interactively →