PKIG

Across TCGA cell cohorts, PKIG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,495 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PKIG-associated GO terms across cancer lineages are Positive regulation of supramolecular fiber organization, Positive regulation of cytoskeleton organization, and Negative regulation of polyamine transmembrane transport. Each is linked with PKIG in more than 14 cancer types. Because this analysis shows association rather than direction, both PKIG-to-partner and partner-to-PKIG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of supramolecular fiber organization grouped by PKIG-low versus PKIG-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKIG→partner) and Y-score (partner→PKIG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of supramolecular fiber organization →	+0.113	+1.008	<.001	.003	3	15
LIVER	Positive regulation of cytoskeleton organization →	+0.079	+0.918	.002	.004	3	11
LUNG_NSCLC_LUSC	Negative regulation of polyamine transmembrane transport →	+0.127	+1.777	<.001	<.001	3	11
BONE	Collagen biosynthetic process →	+0.225	+1.065	.001	.003	3	11
LUNG_NSCLC_LUAD	Protein localization to cilium →	+0.049	+1.221	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Response to oscillatory fluid shear stress →	+0.120	+1.341	.005	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,495 associations by consensus.

Positive regulation of supramolecular fiber organization by PKIG expression — LIVER

Explore this box plot interactively →