PKIB

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PKIB mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PKIB-associated genes across cancer lineages are Macrophages. Each is linked with PKIB in more than 1 cancer types. Because this analysis shows association rather than direction, both PKIB-to-partner and partner-to-PKIB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macrophages grouped by PKIB-low versus PKIB-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PKIB→partner) and Y-score (partner→PKIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMacrophages →+0.039+3.288<.001.04131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Macrophages by PKIB expression — COAD

Box plot of Macrophages in PKIB-low vs PKIB-high samples in COAD.

Explore this box plot interactively →

Exploration