PKIA

Across TCGA patient cohorts, PKIA RNA expression is significantly associated with the protein abundance of many other proteins, with 17,380 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PKIA-associated proteins across cancer lineages are ZC2HC1A, BDH2, and GTPBP10. Each is linked with PKIA in more than 5 cancer types. Because this analysis shows association rather than direction, both PKIA-to-partner and partner-to-PKIA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKIA versus ZC2HC1A in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKIA→partner) and Y-score (partner→PKIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZC2HC1A →	+0.415	+1.328	<.001	<.001	3	6
OV	BDH2 →	+0.484	+0.982	.006	.003	3	5
LSCC	GTPBP10 →	-0.428	-1.090	<.001	<.001	3	5
HNSC	MAP4 →	+0.418	+1.300	<.001	<.001	3	5
UCEC	TRIO_S1724 →	+0.495	+0.748	.001	.002	3	5
COAD	PGM1 →	+0.400	+0.895	.006	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,380 associations by consensus.

PKIA vs ZC2HC1A — HNSC

Explore this scatter interactively →