Across TCGA cell cohorts, PKHD1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,599 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PKHD1L1-associated GO terms across cancer lineages are Regulation of transcription elongation by RNA polymerase II, Positive regulation of transcription initiation by RNA polymerase II, and RNA polymerase II preinitiation complex assembly. Each is linked with PKHD1L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PKHD1L1-to-partner and partner-to-PKHD1L1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKHD1L1→partner) and Y-score (partner→PKHD1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of transcription elongation by RNA polymerase II →	+0.042	+0.041	<.001	.009	2	8
CNS	Positive regulation of transcription initiation by RNA polymerase II →	+0.039	+0.096	.003	.005	3	6
PANCREAS	RNA polymerase II preinitiation complex assembly →	+0.045	+0.129	.004	.008	3	5
BLOOD_Lymphoma	Immune response to tumor cell →	-0.219	-2.861	<.001	<.001	3	5
LIVER	Regulation of respiratory gaseous exchange →	+0.194	+0.164	<.001	.001	3	5
BREAST	Response to triglyceride →	-0.185	-0.316	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,599 associations by consensus.

Exploration

PKHD1L1 survival (RNA) · tumor vs normal (RNA) · all PKHD1L1 data types