PKDREJ

Across TCGA cell cohorts, PKDREJ RNA expression is significantly associated with the go_rna of many other GO terms, with 2,272 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PKDREJ-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of myoblast fusion. Each is linked with PKDREJ in more than 11 cancer types. Because this analysis shows association rather than direction, both PKDREJ-to-partner and partner-to-PKDREJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by PKDREJ-low versus PKDREJ-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKDREJ→partner) and Y-score (partner→PKDREJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+0.218	<.001	.002	3	12
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.079	+0.218	<.001	.002	3	12
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.076	+0.211	<.001	.003	3	10
OESOPHAGUS	Endosomal transport →	+0.047	+0.204	.002	<.001	3	9
CNS	Cytoplasmic translation →	+0.056	+0.082	<.001	.001	3	9
BONE	Cilium or flagellum-dependent cell motility →	-0.071	-0.133	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,272 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by PKDREJ expression — BLOOD_Lymphoma

Explore this box plot interactively →